Modafinil falls within the of the Schedule IV on the DEA drug list. Modafinil is a stimulant used to improve wakefulness in patients with sleep apnea, narcolepsy, or shift work disorder. Modafinil is a stimulant drug marketed as a ‘wakefulness promoting agent’ and is one of the stimulants used in the treatment of narcolepsy.
Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. The prexin neuron activation is associated with psychoactivation and euphoria.
The exact mechanism of action is unclear, although in vitro studies have shown it to inhibit the reuptake of dopamine by binding to the dopamine reuptake pump, and lead to an increase in extracellular dopamine. Modafinil activates glutamatergic circuits while inhibiting GABA.
Modafinil is a Schedule IV which means it is . Other drugs like Xanax, serdexmethylphenidate, Soma, Darvon, Darvocet, Valium, Ativan, Talwin, Ambien, Mazindol, Tramadol in the same class at random are also classified as Schedule IV by the DEA.
Modafinil is a Small Molecule that is categorized for Approved, Investigational but can be dangerous when used recreationally or misused.Lifespan Of Modafinil In The Human Body
The half-life of Modafinil means the amount of time that stays in your system before it is fully absorbed. The half-life of Modafinil is The normal half-life of modafinil in humans is between 12 to 15 hours.
Modafinil is sold under a wide variety of brand names worldwide, including:
To improve wakefulness in patients with excessive daytime sleepiness (EDS) associated with narcolepsy. It is also used during detox to treat cocaine addiction.
Modafinil is a stimulant drug marketed as a ‘wakefulness promoting agent’ and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. The prexin neuron activation is associated with psychoactivation and euphoria.
Modafinil is not indicated for complaints of lack of energy or fatigue; but it appears to be very helpful for some patients. Also, it has been used in the treatment of hypersomnia, a disorder in which patients lack the capacity for meaningful sleep and may require ten or more hours per day. Recent studies have have found that modafinil may help recovering cocaine addicts fight their addiction.
Drug name is Modafinil is a stimulant used to improve wakefulness in patients with sleep apnea, narcolepsy, or shift work disorder. which is different from because Modafinil is a stimulant used to improve wakefulness in patients with sleep apnea, narcolepsy, or shift work disorder.
Modafinil is not commonly addictive. There have been reports of Modafinil addiction, however, it is actually used in addiction treatment for individuals that have become dependent on cocaine. Modafinil reduces cocaine dependence and withdrawal phenomenon.
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Mayo Foundation for Medical Education and Research. (2022, November 1). Modafinil (oral route) side effects. Mayo Clinic. Retrieved December 22, 2022, from https://www.mayoclinic.org/drugs-supplements/modafinil-oral-route/side-effects/drg-20064870
Alacam, H., Basay, O., Tumkaya, S., Mart, M., & Kar, G. (2018). Modafinil dependence: a case with attention-deficit/hyperactivity disorder. Psychiatry Investigation, 15(4), 424.
Volkow, N. D., Fowler, J. S., Logan, J., Alexoff, D., Zhu, W., Telang, F., Wang, G.-J., Jayne, M., Hooker, J. M., Wong, C., Hubbard, B., Carter, P., Warner, D., King, P., Shea, C., Xu, Y., Muench, L., & Apelskog-Torres, K. (2009). Effects of modafinil on dopamine and dopamine transporters in the male human brain. JAMA, 301(11), 1148.
D’Souza, P. D., & Mascarenhas, J. J. (2019). A case report on modafinil dependence. Galore Int J Health Sci Res, 4(3), 8-11.
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Dr. Bickley graduated from U.C. Irvine with honors: Phi Beta Kappa, Golden Key International Honor Society, Cum Laude. He has been featured on national radio and print media. He is also a frequent lecturer at National Conferences. He holds an A.S. degree in Drug & Alcohol Studies, and two B.A. degrees in Criminology & Psychology, and masters and doctoral degree in Clinical Psychology. He is a licensed California Drug & Alcohol Counselor Level II, a licensed Clinical Supervisor and is certified in treating Eating Disorders.
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